Email: gary.reynolds@ncl.ac.uk

Research profile and key clinical specialties

My research focuses on applying inflammatory diseases alongside clinical interpretation to high dimensional multi-omic data, particularly single cell C.

I am a consultant Rheumatologist with an interest in vasculitis, particularly Giant Cell Arteritis. My previous research has applied these approaches to a range of clinical conditions, including inflammatory skin disorders where we identify re-emergence of cell states from early development in disease and in COVID-19, where we characterise the peripheral blood immune response.

Two key publications

• Reynolds G, Vegh P, Fletcher J, Poyner EFM,…,Haniffa M. Developmental cell programs are co-opted in inflammatory skin disease. Science. 2021 Jan 22;371(6527):eaba6500. doi: 10.1126/science.aba6500.
• Stephenson E, Reynolds G, Botting RA, Calero-Nieto FJ, Morgan MD, Tuong ZK, Bach K, Sungnak W, Teichmann SA, Clatworthy MR, Marioni JC, Göttgens B, Haniffa M. Single-cell multi-omics analysis of the immune response in COVID-19. Nat Med. 2021 May;27(5):904-916. doi: 10.1038/s41591-021-01329-2.

Possible PhD projects

Applying single cell genomics to human inflammatory diseases.

Keywords: Rheumatologist, rheumatology, Inflammatory, diseases, omics,, skin, disorders, COVID-19, blood immune response, Gary, Reynolds, Newcastle

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