Email: s.foster@sheffield.ac.uk

Research profile and key clinical specialties

The research in my lab encompasses microbiology from cell structure and biochemistry through to cell growth and division using a range of approaches including super resolution microscopy.

This is complemented by an array of studies into host pathogen interaction using several in vivo models.

In particular the research focuses on the human, antibiotic resistant, pathogen Staphylococcus aureus.

Two key publications

• Panchal, V. V., Griffiths, C., Mosaei, H., Bilyk, B., Sutton, J., Carnell, O. T., Hornby, D. P., Green, J., Hobbs, J. K., Kelley, W. L., Zenkin, N., & Foster, S. J. (2020). Evolving MRSA: High-level β-lactam resistance in Staphylococcus aureus is associated with RNA Polymerase alterations and fine tuning of gene expression. PLoS Pathogens, 16(7), e1008672.
• Boldock, E., Surewaard, B.G.J., Shamarina, D., Na, M., Fei, Y., Ali, A., Williams, A., Pollitt, E.J.G., Szkuta, P., Morris, P., Prajsnar, T.K., McCoy, K.D., Jin, T., Dockrell, D.H., van Strijp, J.A.G., Kubes, P., Renshaw, S.A. & Foster, S.J. (2018) Human skin commensals augment Staphylococcus aureus pathogenesis. Nature Microbiology doi: 10.1038/s41564-018-0198-3.

Possible PhD projects

• Mechanisms of antibiotic resistance
• Action of antibiotics

More information

• The Florey Institute
• The Foster Lab

Keywords: Biochemistry, microscopy, human, antibiotic resistant, pathogen Staphylococcus aureus, Simon, Foster, Sheffield

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