Email: M.J.Cork@sheffield.ac.uk

Research profile and key clinical specialties

Sheffield Research (SDR) is focused on research to develop and bring-to-clinic, new treatments for atopic dermatitis/eczema (AD).

Our research spans from the prevention of AD to the development and testing (in clinical trials) of innovative new medicines to treat AD.

A major focus is on how topical wash products, emollients, oils, and water itself, affect the skin barrier and how this leads to the development of AD.

This is helping to identify treatment approaches with the optimum effect on the development and maintenance of the skin barrier.

Two key publications

• Danby SG, Andrew PV, Brown K, Chittock J, Kay LJ, Cork MJ. An Investigation of the Skin Barrier Restoring Effects of a Cream and Lotion Containing Ceramides in a Multi-vesicular Emulsion in People with Dry, Eczema-Prone, Skin: The RESTORE Study Phase 1. Dermatol Ther (Heidelb). 2020 Oct;10(5):1031-1041. doi: 10.1007/s13555-020-00426-3. PMID: 32671664
• Cork MJ, Danby SG, Ogg GS. Atopic dermatitis epidemiology and unmet need in the United Kingdom. J Dermatolog Treat. 2020 Dec;31(8):801-809. doi: 10.1080/09546634.2019.1655137. Epub 2019 Oct 21. PMID: 31631717

More information

• Sheffield Dermatology Research
• Dermatology research at Sheffield

Keywords: Gene, nervous, therapy, motor neuron, dopamine, Parkinson’s, C9orf72, PTEN, spinal, genome, Mimoun, Azzouz, Sheffeld

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